Zyloric 100 Tablet

Skin rash, nausea, vomiting, diarrhoea, abdominal pain, headache, drowsiness, dizziness, raised liver enzymes

Risk of serious hypersensitivity reactions (e.g., severe skin rash/Stevens-Johnson syndrome/TEN); stop and seek urgent care if rash, fever, mouth sores or swelling occurs. Dose adjustment is needed in kidney impairment; monitor kidney function, liver enzymes and blood counts as advised. Start with low dose and titrate to reduce gout flare risk; prophylaxis with NSAID/colchicine may be recommended initially. Use caution in liver disease. Inform doctor if you have HLA-B*58:01 risk (higher risk in some Asian populations) or history of allopurinol allergy.

Azathioprine, mercaptopurine (severe toxicity—dose adjustment/avoid), warfarin (increased anticoagulant effect), theophylline, didanosine, ampicillin/amoxicillin (increased rash risk), thiazide diuretics (increased hypersensitivity risk), ACE inhibitors (increased hypersensitivity risk), ciclosporin, cyclophosphamide

Store at room temperature (below 25°C), in a dry place away from moisture and direct light. Keep out of reach of children.

Allopurinol 100 mg Tablet (generic), Aloric 100 Tablet, Zyloprim 100 Tablet, Lopurin 100 Tablet, Allopurinol IP 100 mg Tablet