Zukanorm M 500 Tablet

Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, flatulence, headache

Risk of lactic acidosis (rare but serious) especially with kidney impairment, dehydration, severe infection, shock, heavy alcohol use, or heart/liver failure—seek urgent care for rapid breathing, severe weakness, abdominal pain, or drowsiness. Dose adjustment/avoid in reduced kidney function; periodic eGFR monitoring needed. Stop temporarily before iodinated contrast imaging and major surgery as advised. Long-term use may cause vitamin B12 deficiency; monitor if anaemia/neuropathy. Not for type 1 diabetes or diabetic ketoacidosis.

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cimetidine, diuretics, corticosteroids, thyroid hormones, sympathomimetics, antipsychotics (e.g., olanzapine), other antidiabetic medicines/insulin (may increase hypoglycaemia risk when combined)

Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.

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