Not recommended in patients with active peptic ulcer/bleeding, severe heart failure, or hypersensitivity to NSAIDs. Use with caution in history of ulcer, bleeding disorders, kidney/liver impairment, asthma, hypertension, cardiovascular disease, and in the elderly. May increase risk of GI bleeding, kidney injury, fluid retention and cardiovascular thrombotic events with prolonged use. Stop and seek care if black stools, vomiting blood, severe abdominal pain, yellowing of eyes/skin, or allergic reactions occur. Do not exceed total daily paracetamol limits; avoid prolonged self-medication.