Risk of hypoglycaemia, especially if meals are skipped, with alcohol use, or with other anti-diabetics/insulin. Use caution in kidney or liver disease; dose adjustments/avoidance may be needed depending on ingredients. Inform doctor if you have heart disease, dehydration, severe infection, or are undergoing surgery; some diabetes medicines may need temporary stoppage. Seek urgent care for severe low sugar (confusion, sweating, fainting) or allergic reactions.