Pregnancy:Use with caution / Consult doctor (generally not recommended unless clearly needed)
Alcohol:Avoid (treatment is intended to support abstinence; alcohol use may worsen outcomes)
Overview
Drug | Tablet
Uses & Benefits
Maintenance of abstinence in alcohol dependence/alcohol use disorder (as part of a comprehensive program including counseling and psychosocial support)
How It Works
Acamprosate modulates neurotransmission in the brain by reducing glutamatergic hyperexcitability and helping restore the balance between excitatory (glutamate) and inhibitory (GABA) pathways disrupted by chronic alcohol use. This reduces post-withdrawal cravings and discomfort, supporting continued abstinence.
Frequently Asked Questions
What is this medicine used for?
Maintenance of abstinence in alcohol dependence/alcohol use disorder (as part of a comprehensive program including counseling and psychosocial support)
What are the side effects?
Diarrhea, nausea, vomiting, abdominal pain, flatulence, loss of appetite, headache, dizziness, insomnia, anxiety, itching/rash, fatigue
How does this medicine work?
Acamprosate modulates neurotransmission in the brain by reducing glutamatergic hyperexcitability and helping restore the balance between excitatory (glutamate) and inhibitory (GABA) pathways disrupted by chronic alcohol use. This reduces post-withdrawal cravings and discomfort, supporting continued abstinence.
How should I use this medicine?
Use as prescribed by a doctor. Typically started after alcohol detoxification/when abstinent. Tablets are swallowed whole with water; can be taken with or without food (taking with meals may improve tolerance). Do not crush/chew unless advised. Dose adjustment may be needed in kidney impairment.
How should I store this medicine?
Store at room temperature (below 25°C), in a dry place, protected from moisture and light. Keep out of reach of children.
Disclaimer
Product information is for awareness only and does not replace medical advice. Do not self-medicate for serious symptoms. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling/prescribing information, established medical literature, standard pharmacology references, CDSCO/drug safety updates
Availability depends on stock and serviceability.
Directions for Use
Use as prescribed by a doctor. Typically started after alcohol detoxification/when abstinent. Tablets are swallowed whole with water; can be taken with or without food (taking with meals may improve tolerance). Do not crush/chew unless advised. Dose adjustment may be needed in kidney impairment.
Side Effects
Diarrhea, nausea, vomiting, abdominal pain, flatulence, loss of appetite, headache, dizziness, insomnia, anxiety, itching/rash, fatigue
Warnings & Precautions
Not for treating acute alcohol withdrawal—use only to maintain abstinence. Avoid/use with caution in renal impairment; contraindicated in severe kidney disease. Use caution in depression or suicidal thoughts—monitor mood/behavior. If relapse occurs, continue only as advised by clinician along with counseling. Inform doctor about all medicines and medical conditions.
Drug Interactions
No major clinically significant interactions are common; however inform your doctor if taking naltrexone, disulfiram, antidepressants, antipsychotics, sedatives, or other CNS-acting medicines. Additive gastrointestinal effects may occur with drugs causing diarrhea.
Storage Instructions
Store at room temperature (below 25°C), in a dry place, protected from moisture and light. Keep out of reach of children.
